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dc.contributor.authorParra Jaimes, Julian David.-
dc.date.accessioned2022-05-13T02:57:13Z-
dc.date.available2018-09-15-
dc.date.available2022-05-13T02:57:13Z-
dc.date.issued2018-
dc.identifier.citationParra Jaimes, J. D. (2018). Linfoma linfoblástico difuso multicéntrico de alto grado en un canino [Trabajo de Grado Pregrado, Universidad de Pamplona]. Repositorio Hulago Universidad de Pamplona. http://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/736es_CO
dc.identifier.urihttp://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/736-
dc.descriptionSe presentó el caso clínico de un canino con linfoma linfoblástico difuso multicéntrico de alto grado, diagnosticado gracias al examen físico, estudios hematológicos, citológicos e histopatológicos y ultrasonográficos realizados en la Clínica Veterinaria de Pequeños Animales MascoVet Cúcuta – Colombia. El paciente ingresó a consulta por aumento de tamaño y dolor a la palpación en la región submandibular, escapular y a nivel caudal de los miembros posteriores relacionados a la ubicación de los linfonodos. Se le realizó examen clínico, cuadros hematológicos, bioquímicas sanguíneas, ultrasonografía, citología e histopatología. Los hallazgos más relevantes fueron linfadenomegalia submandibular, pre-escapular, poplítea superficial e iliaca media bilateral, esplenomegalia, mediante palpación y ultrasonografía. Bicitopenia por leucopenia (neutrofilia y linfopenia) y trombocitopenia, hipoproteinemia mediante hematología. Linfoma mediante citología. Por histopatología, tumor maligno de células redondas: linfoma linfoblástico difuso de alto grado. Se trató con el protocolo CHOP de 19 semanas de la Universidad de Wisconsin-Madison para perros. El paciente presentó respuesta completa a partir de la primera semana de CHOP y se mantuvo estable hasta la cuarta semana, donde posterior a la aplicación de Doxorrubicina y baja en la posología de Prednisolona el paciente se desestabilizó manifestando vómitos frecuentes y decaimiento, signos que llevaron al propietario a desistir de la quimioterapia.es_CO
dc.description.abstractThe clinical case of a canine with high-grade multicentric diffuse lymphoblastic lymphoma is presented, diagnosed through physical examination, hematological, cytological and histopathological and ultrasonographic studies carried out at the Veterinary Clinic of Small Animals MascoVet, Cúcuta - Colombia. The patient was admitted due to enlargement and pain on palpation in the submandibular, scapular region and caudal level of the posterior limbs compatible with the location of the lymph nodes. He underwent clinical examination, hematological, blood biochemistry, ultrasonography, cytology and histopathology. The most relevant findings were submandibular lymphadenomegaly, pre-scapular, superficial popliteal and bilateral middle iliac, splenomegaly, by palpation and ultrasonography. Bicitopenia due to leukopenia (neutrophilia and lymphopenia) and thrombocytopenia, hypoproteinemia by hematology. Lymphoma by cytology. By histopathology, malignant tumor of Round cells: high- grade diffuse lymphoblastic lymphoma. It was treated with the 19-week CHOP protocol from the University of Wisconsin-Madison for dogs. The patient presented a complete response of the first week of CHOP and remained stable until the fourth week, where after the application of Doxorubicin and low in the dose of Prednisolone the patient was destabilized, manifesting frequent vomiting and decay, signs that led to the owner to desist from chemotherapy.es_CO
dc.format.extent113es_CO
dc.format.mimetypeapplication/pdfes_CO
dc.language.isoeses_CO
dc.publisherUniversidad de Pamplona – Facultad de Ciencias Agrarias.es_CO
dc.subjectLinfoma.es_CO
dc.subjectLinfadenomegalia.es_CO
dc.subjectUltrasonografía.es_CO
dc.subjectItología.es_CO
dc.subjectHistopatología.es_CO
dc.subjectCHOP.es_CO
dc.titleLinfoma linfoblástico difuso multicéntrico de alto grado en un canino.es_CO
dc.typehttp://purl.org/coar/resource_type/c_7a1fes_CO
dc.date.accepted2018-06-15-
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