Obtención de extracto crudo y refinado a partir de Cannabis SP. Con las características de interés para la Industria Farmacéutica en las instalaciones de Pétalo Pharmaceutical S.A.S.

Abstract

Scientifi advances that demonstrate the potential for the use of cannabis for various symptoms and palliative treatments have caused several countries to regulate its production and consumption for medical and scientifi purposes under quality and safety standards that can be found in pharmacopeias. The compounds of greatest interest for medicinal purposes in cannabis are cannabidiol (CBD) and tetrahydrocannabinol (THC) which, present in the species Cannabis sp. They can be supplied to patients in the form of dried flwers (cannabis), extracts, tinctures, etc. Cannabis extractions for the manufacture of medicines must meet quality and safety standards that start from the cannabis to be used as raw material, processing plants, quality control, and regulatory affirs. This document describes the raw material, the extraction-distillation methods, and other unit operations used to obtain crude and refied cannabis extract with characteristics similar to raw materials on the international market. The methodology is also shown with the respective parameters and operating conditions used, which were selected based on the literature. The results show high yields with the selected operating conditions.