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dc.contributor.authorMarquez Arenas, Brian Esteban.-
dc.date.accessioned2026-11-06T16:11:01Z-
dc.date.available2025-
dc.date.available2026-11-06T16:11:01Z-
dc.date.issued2025-
dc.identifier.citationMárquez Arenas,, B. E. (2025). Hallazgos Histopatológicos De Enterocolitis Necrotizante Asociada A Salmonella Spp. En Pitón India Albina (Python Molurus) En Cautiverio Sin Periodo De Brumación. Reporte De Caso [Trabajo de Grado Pregrado, Universidad de Pamplona]. Repositorio Hulago Universidad de Pamplona. https://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/12260es_CO
dc.identifier.urihttps://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/12260-
dc.descriptionUna pitón india (Python molurus) albina adulta mantenida en cautiverio en el zoológico local Zoo São Braz, Santa María, Brasil, fue remitida para atención veterinaria por signos respiratorios y apatía. La paciente presentó inicialmente respuesta parcial al tratamiento antibiótico y antiinflamatorio, sin embargo, recayó clínicamente y fue hallada muerta tras aproximadamente un mes de evolución. En la necropsia se observaron alteraciones cutáneas multifocales, contenido espumoso pulmonar y recubrimiento pseudomembranoso difuso en intestino grueso. El estudio histopatológico reveló necrosis extensa de mucosa intestinal, inflamación heterofilia predominante, formación granulomatosa y presencia de bacilos intralesionales morfológicamente compatibles con Salmonella sp. Los cultivos bacterianos confirmaron el crecimiento de cocobacilos Gram negativos, enviados posteriormente para serotipificación. Se discute la relación del agente con la inmunosupresión vinculada a la falta de brumación, y se resalta la importancia del diagnóstico histopatológico en reptiles de zoológico.es_CO
dc.description.abstractAn adult albino Indian python (Python molurus) kept in captivity at the local Zoo São Braz, Santa Maria, Brazil, was referred for veterinary care due to respiratory signs and apathy. The patient initially showed a partial response to antibiotic and anti-inflammatory treatment; however, it later relapsed clinically and was found dead after approximately one month of progression. Necropsy revealed multifocal cutaneous lesions, foamy pulmonary content, and a diffuse pseudomembranous coating in the large intestine. Histopathological examination showed extensive intestinal mucosal necrosis, predominantly heterophilic inflammation, granulomatous formation, and the presence of intralesional bacilli morphologically compatible with Salmonella sp. Bacterial cultures confirmed the growth of Gram-negative coccobacilli, which were subsequently submitted for serotyping. The relationship between the pathogen and immunosuppression associated with the lack of brumation is discussed, and the importance of histopathological diagnosis in zoo reptiles is emphasized.es_CO
dc.format.extent49es_CO
dc.format.mimetypeapplication/pdfes_CO
dc.language.isoeses_CO
dc.publisherUniversidad de Pamplona - Facultad de Ciencias Agrarias.es_CO
dc.subjectReptiles.es_CO
dc.subjectPitón india.es_CO
dc.subjectSalmonella sp.es_CO
dc.subjectEnterocolitis necrotizante.es_CO
dc.subjectHistopatología.es_CO
dc.titleHallazgos Histopatológicos De Enterocolitis Necrotizante Asociada A Salmonella Spp. En Pitón India Albina (Python Molurus) En Cautiverio Sin Periodo De Brumación. Reporte De Caso.es_CO
dc.typehttp://purl.org/coar/resource_type/c_7a1fes_CO
dc.date.accepted2025-
dc.relation.referencesAndino, A., & Hanning, I. (2015). Salmonella enterica: survival, colonization, and virulence differences among serovars. TheScientificWorldJournal, 2015, 520179. https://doi.org/10.1155/2015/520179.es_CO
dc.relation.referencesAngilletta, J., Michael, J. (2009). Thermal Adaptation: A Theoretical and Empirical Synthesis. Oxford University Press. https://doi.org/10.1093/acprof:oso/9780198570875.001.1.es_CO
dc.relation.referencesBertolini, M., Schwertz, C. I., Vielmo, A., Piva, M. M., Bilhalva, L. C., Pavarini, S. P., Driemeier, D., & Sonne, L. (2021). Pathological and microbiological findings in fatal cases of salmonellosis in captive Bothrops snakes in Southern Brazil. Journal of Comparative Pathology, 186, 7–12. https://doi.org/10.1016/j.jcpa.2021.04.011.es_CO
dc.relation.referencesBjelland, A. M., Sandvik, L. M., Skarstein, M. M., Svendal, L., & Debenham, J. J. (2020). Prevalence of Salmonella serovars isolated from reptiles in Norwegian zoos. Acta veterinaria Scandinavica, 62(1), 3. https://doi.org/10.1186/s13028-020-0502-0.es_CO
dc.relation.referencesBrenner, F., Villar, R., Angulo, F., Tauxe, R., Swaminathan, B. (2000). Salmonella Nomenclature. J Clin Microbiol 38. https://doi.org/10.1128/jcm.38.7.2465-2467.2000.es_CO
dc.relation.referencesde Souza, S. O., Casagrande, R. A., Guerra, P. R., Cruz, C. E., Veit, E., Cardoso, M. R., & Driemeier, D. (2014). Osteomyelitis caused by Salmonella enterica serovar derby in boa constrictor. Journal of zoo and wildlife medicine: official publication of the American Association of Zoo Veterinarians, 45(3), 642–644. https://doi.org/10.1638/2013-0050R2.1.es_CO
dc.relation.referencesFlanders, A. J., Ossiboff, R. J., Wellehan, J. F. X. Jr., Alexander, A. B., Fredholm, D. V. E., Desiderio, T. M., & Stacy, N. I. (2021). Presumptive heterophil extracellular traps recognized cytologically in nine reptile patients with inflammatory conditions. Veterinary Quarterly, 41(1), 89-96. https://doi.org/10.1080/01652176.2021.1873453.es_CO
dc.relation.referencesGordon, D. M., & Cowling, A. (2003). The distribution and genetic structure of Escherichia coli in Australian vertebrates: Host and geographic effects. Microbiology, 149(12), 3575–3586. https://doi.org/10.1099/mic.0.26486-0.es_CO
dc.relation.referencesGreene, H. (1997). Snakes: The Evolution of Mystery in Nature. Berkeley: University of California Press. ISBN 0-520- 20014-4.es_CO
dc.relation.referencesGrimont, P. A., & Weill, F. X. (2007). Antigenic formulae of the Salmonella serovars (9th ed.). WHO Collaborating Centre/Institut Pasteur. (PDF) https://www.scacm.org/free/Antigenic%20Formulae%20of%20the%20Salmonella%20Serovars%202007%209th%20edition.pdf.es_CO
dc.relation.referencesHoekstra, L. A., Schwartz, T. S., Sparkman, A. M., Miller, D. A. W., & Bronikowski, A. M. (2020). The untapped potential of reptile biodiversity for understanding how and why animals age. Functional ecology, 34(1), 38–54. https://doi.org/10.1111/1365-2435.13450.es_CO
dc.relation.referencesJacobson, E.R. (Ed.). (2007). Infectious Diseases and Pathology of Reptiles: Color Atlas and Text (1st ed.). CRC Press. https://doi.org/10.1201/9781420004038es_CO
dc.relation.referencesKim, G. R., Kim, S. H., Kim, E. Y., Park, E. H., Hwang, I. Y., Jeong, S. H., Kim, H. S., Kim, Y. A., Uh, Y., Shin, K. S., Kim, Y. R., Ryoo, N., Shin, J. H., & Shin, J. H. (2022). Performance of MALDI-TOF Mass Spectrometry (VITEK MS) in the Identification of Salmonella Species. Microorganisms, 10(10), 1974. https://doi.org/10.3390/microorganisms10101974.es_CO
dc.relation.referencesKsiążczyk, M., Wasyl, D., Szczerba-Turek, A., Dominiak-Górski, B., & Skarżyńska, M. (2021). Characteristics of Escherichia coli isolated from reptiles in Poland. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms22031192.es_CO
dc.relation.referencesLillywhite, H. (2014). How snakes work: Structure, function and behavior of the world’s snakes. Oxford University Press. ISBN 978-0-19-538037-8.es_CO
dc.relation.referencesLou, L., Zhang, P., Piao, R., & Wang, Y. (2019). SPI-1 and its complex regulation in Salmonella. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2019.00270.es_CO
dc.relation.referencesde Freitas, R. M., de Oliveira, H. S., Duarte, J. L., Júnior, F., de Sousa, T., Dos Santos, K. M., da Silva, E., da Silva, N., de Oliveira, C. J., de Araújo, J., & de Souza, F. (2024). Fibrinonecrotic enteritis and orchitis associated with Salmonella enterica subsp houtenae infection in a short-tailed boa (Boa constrictor amarali). Journal of comparative pathology. https://doi.org/10.1016/j.jcpa.2024.01.002.es_CO
dc.relation.referencesMeletiadis, A., Romano, A., Moroni, B., Di Nicola, M. R., Montemurro, V., Pitti, M., Pezzolato, M., Bozzetta, E., Sciuto, S., & Acutis, P. L. (2024). A case of food-borne salmonellosis in a corn snake (Pantherophis guttatus) after a feeder mouse meal. Animals, 14(12), 1722. https://doi.org/10.3390/ani14121722.es_CO
dc.relation.referencesMeylan, S., Haussy, C., & Voituron, Y. (2010). Physiological actions of corticosterone and its modulation by an immune challenge in reptiles. General and Comparative Endocrinology, 169(1), 158–166. https://doi.org/10.1016/j.ygcen.2010.08.002.es_CO
dc.relation.referencesMitchell, M. A. (2012). Mycobacterial infections in reptiles. Veterinary Clinics of North America: Exotic Animal Practice, 15(1), 101-111. https://doi.org/10.1016/j.cvex.2011.10.002.es_CO
dc.relation.referencesOludairo, O., Kwaga, J., Kabir, J., Abdu, P., Gitanjali, A., et al. (2022). A Review on Salmonella Characteristics, Taxonomy, and Pathogenesis. Zagazig Veterinary Journal. DOI: 10.21608/zvjz.2022.137946.1179.es_CO
dc.relation.referencesPees, M., Menke, M., & Pasmans, F. (2023). Salmonella in reptiles: occurrence, interactions, shedding and risk factors for human infections. Frontiers in Cellular and Infection Microbiology, Vol 11. https://doi.org/10.3389/fcell.2023.1251036.es_CO
dc.relation.referencesPereira, R. M. F., de Oliveira Filho, H. S., Duarte, J. L. C., Júnior, F. R. P., Lima, T. S., dos Santos, K. M. O. L., Pereira, E. S., da Silva, N. J., de Oliveira, C. J. B., de Araújo, J. L., & Mendonça, F. S. (2024). Fibrinonecrotic enteritis and orchitis associated with Salmonella enterica subsp houtenae infection in a short-tailed boa (Boa constrictor amarali). Journal of Comparative Pathology. https://doi.org/10.1016/j.jcpa.2023.09.006 Pough, F. H., Andrews, R. M., Cadle, J. E., Crump, M. L., Savitzky, A. H., & Wells, K. D. (2015).Herpetology (4th ed.). Sinauer/Oxford University Press. ISBN: 978-1605352336.https://global.oup.com/ushe/product/herpetology-9781605352336?q=pough&cc=us&lang=en.es_CO
dc.relation.referencesRamsay, E. C., Daniel, G. B., Tryon, B. W., Merryman, J. I., Morris, P. J., & Bemis, D. A. (2002). Osteomyelitis associated with Salmonella enterica SS arizonae in a colony of ridgenose rattlesnakes (Crotalus willardi). Journal of zoo and wildlife medicine: official publication of the American Association of Zoo Veterinarians, 33(4), 301–310. https://doi.org/10.1638/1042-7260(2002)033[0301:OAWSES]2.0.CO;2.es_CO
dc.relation.referencesRen J, Xia J, Zhang M, Liu C, Xu Y, Wu J, Li Y, Zhou M, Li S, Cao W. (2025). Automated identification of Salmonella serotype using MALDI-TOF mass spectrometry and machine learning techniques. J Clin Microbiol63:e00037-25. https://doi.org/10.1128/jcm.00037-25.es_CO
dc.relation.referencesSakaguchi, K., Nevarez, J. G., & Del Piero, F. (2017). Salmonella Enterica Serovar Pomona Infection in Farmed Juvenile American Alligators (Alligator Mississippiensis). Veterinary Pathology. https://doi.org/10.1177/0300985816677149.es_CO
dc.relation.referencesSandmeier, F. C., Tracy, C. R., Dupré, S., & Hunter, K. (2012). A trade-off between natural and acquired antibody production in reptile: implications for long-term resistance to disease. Biology open, 1(11), 1078–1082. https://doi.org/10.1242/bio.20122527.es_CO
dc.relation.referencesSchmidt, V., Mock, R., Burgkhardt, E. et al. Cloacal Aerobic Bacterial Flora and Absence of Viruses in Free-Living Slow Worms (Anguis fragilis), Grass Snakes (Natrix natrix) and European Adders (Vipera berus) from Germany. EcoHealth 11, 571–580 (2014). https://doi.org/10.1007/s10393-014-0947-6es_CO
dc.relation.referencesSecor, S. M., & Diamond, J. (1997). Effects of meal size on postprandial responses in juvenile Burmese pythons (Python molurus). The American journal of physiology, 272(3 Pt 2), R902–R912. https://doi.org/10.1152/ajpregu.1997.272.3.R902.es_CO
dc.relation.referencesSingh, J., Mallik, S., Nath, I., Acharya, A., Das, S. P., Sethi, S., & Sahoo, M. (2018). Infectious stomatitis in an Indian rock python (Python molurus) and its therapeutic management. Journal of Entomology and Zoology Studies, 6(4), 392–394. https://www.entomoljournal.com/archives/2018/vol6issue4/PartH/6-3-167-543.pdf.es_CO
dc.relation.referencesSouza, B. C., Cavasani, J. P. S., Santos, I. G., Sabino, L., Ubiali, D. G., Pescador, C. A., Colodel, E. M., & Furlan, F. H. (2025). Mortality by Entamoeba invadens in green anacondas (Eunectes murinus) from a zoological garden. Pesquisa Veterinária Brasileira, 45, e07585. https://doi.org/10.1590/1678-5150-PVB-7585.es_CO
dc.relation.referencesStarck, J. M., & Wimmer, C. (2004). Pythons metabolize prey to fuel the post-feeding response. Proceedings of the Royal Society B. https://doi.org/10.1098/rspb.2004.2681.es_CO
dc.relation.referencesTang, K., Wang, Z., Wan, Q., & Fang, S. (2019). Metagenomics reveals seasonal functional adaptation of the gut microbiome to host feeding and fasting in the Chinese alligator. Frontiers in Microbiology, 10, 2409. https://doi.org/10.3389/fmicb.2019.02409.es_CO
dc.relation.referencesTattersall, G. J., & Ultsch, G. R. (2008). Physiological ecology of aquatic overwintering. Biological Reviews, 83(2), 195–217. https://pubmed.ncbi.nlm.nih.gov/18429765/.es_CO
dc.relation.referencesTracchia, A. C. (2018). Medicina en quelonios y otros reptiles (1ª edicion). Fundación de Historia Natural Félix de Azara / Universidad Maimónides. https://www.fundacionazara.org.ar/img/libros/medicina-de-quelonios.pdf.es_CO
dc.relation.referencesVessieres, F., Cianciolo, R. E., Gkoka, Z. G., Labat, C., Maurey, C., Cadoré, J. L., & Cochelin, L. (2019). Occurrence, management and outcome of immune-complex glomerulonephritis in dogs with suspected glomerulopathy in the UK. Journal of Small Animal Practice. https://doi.org/10.1111/jsap.13065.es_CO
dc.relation.referencesVishnu, C. S., Marshall, B. M., Ramesh, C. et al. (2023). Home range ecology of Indian rock pythons (Python molurus) in Sathyamangalam and Mudumalai Tiger Reserves, Tamil Nadu, Southern India. Sci Rep 13, 9749. https://doi.org/10.1038/s41598-023-36974-9.es_CO
dc.relation.referencesWang, M., Li, H., Liu, R., & Li, J. (2020). Salmonella virulence and immune escape. Microorganisms. https://doi.org/10.3390/microorganisms8030407.es_CO
dc.relation.referencesWeese, J. S., & Staempfli, H. R. (2000). Diarrhea associated with enterotoxigenic Clostridium perfringens in a red-footed tortoise (Geochelone carbonaria). Journal of Zoo and Wildlife Medicine, 31(2), 244–248. doi: 10.1638/1042-7260(2000)031[0265:DAWECP]2.0.CO;2. PMID: 10982148.es_CO
dc.relation.referencesWhitaker, R., & Captain, A. (2004). Snakes of India: The field guide. Draco Books. ISBN-13: 978-8190187305.es_CO
dc.relation.referencesXiong, D., Song, L., Chen, Y., Jiao, X., & Pan, Z. (2023). Salmonella Enteritidis activates inflammatory storm via SPI-1 and SPI-2 to promote intracellular proliferation and bacterial virulence. Frontiers in cellular and infection microbiology, 13, 1158888. https://doi.org/10.3389/fcimb.2023.1158888.es_CO
dc.relation.referencesZając, M., Skarżyńska, M., Lalak, A., Kwit, R., Śmiałowska-Węglińska, A., Pasim, P., Szulowski, K., & Wasyl, D. (2021). Salmonella in captive reptiles and their environment—Can we tame the dragon? Microorganisms, 9(5), 1012. https://doi.org/10.3390/microorganisms9051012.es_CO
dc.relation.referencesZhu, X., Jiang, N., Mai, T., Wu, S., Yao, Y., Du, Y., Lin, C., Lin, L., & Ji, X. (2024). Gut Microbial Communities Are Seasonally Variable in Warm-Climate Lizards Hibernating in the Winter Months. Microorganisms, 12(10), 1974. https://doi.org/10.3390/microorganisms12101974.es_CO
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2es_CO
dc.type.coarversionhttp://purl.org/coar/resource_type/c_2df8fbb1es_CO
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