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dc.contributor.authorMuñoz Monaityama, Albert Andreyt.-
dc.date.accessioned2026-10-24T16:25:29Z-
dc.date.available2024-
dc.date.available2026-10-24T16:25:29Z-
dc.date.issued2024-
dc.identifier.citationMuñoz Monaityama, A. A. (2024). Evaluación de la actividad antimicrobiana de componentes fitoquímicos de un extracto acusoso de la planta medicinal indígena Uitoto Nautilocalyx Pallidus (Sprague) “Kᵻtove” frente a cepas microbianas de colección. [Trabajo de Grado Pregrado, Universidad de Pamplona]. Repositorio Hulago Universidad de Pamplona. https://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/11982es_CO
dc.identifier.urihttps://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/11982-
dc.descriptionNautilocalyx pallidus (Sprague), conocido como “Kᵻtove”, es una planta utilizada en la medicina tradicional indígena de las comunidades uitoto del Amazonas colombiano, especialmente para tratar mordeduras de serpientes venenosas como la equis (Bothrops atrox), la verrugosa (Lachesis muta) y una serpiente conocida comúnmente como serpiente loro (Corallus caninus). Sin embargo, a la fecha no se han realizado investigaciones sobre sus componentes fitoquímicos ni sus posibles propiedades antimicrobianas. Teniendo en cuenta la problemática actual de la multirresistencia antimicrobiana de los microorganismos, el objetivo principal de este estudio fue determinar la efectividad antimicrobiana del extracto acuoso de Nautilocalyx pallidus (Sprague) “Kᵻtove” contra cepas microbianas de la colección ATCC. Para ello, inicialmente se llevó a cabo un análisis fitoquímico cualitativo mediante cromatografía en capa fina, con el fin de identificar los principales compuestos responsables de sus posibles efectos antimicrobianos, seguido de una evaluación de su actividad antimicrobiana contra bacterias Gram-positivas (Staphylococcus aureus, Streptococcus pyogenes), bacterias Gram-negativas (Escherichia coli, Pseudomonas aeruginosa) y una levadura (Candida albicans) empleando la técnica de difusión en pozo. Los resultados del análisis fitoquímico del extracto acuoso de Nautilocalyx pallidus (Sprague) “Kᵻtove” revelaron la presencia de varios compuestos bioactivos que podrían ser responsables de sus propiedades terapéuticas y antimicrobianas. La evaluación de las propiedades antimicrobianas mostró que el extracto puro de la planta no presentó actividad contra Pseudomonas aeruginosa ni Escherichia coli, mientras que tanto, el extracto puro y su dilución al 10% exhibieron actividad antibacteriana contra Staphylococcus aureus y Streptococcus pyogenes; además, el extracto al 10% mostró actividad moderada contra Candida albicanses_CO
dc.description.abstractNautilocalyx pallidus (Sprague), known as “Kᵻtove”, is a plant used in traditional indigenous medicine of the uitoto communities of the Colombian Amazon, especially to treat bites from poisonous snakes such as the horse snake (Bothrops atrox), the warty snake (Lachesis muta) and a snake commonly known as the parrot snake (Corallus caninus). However, to date, no research has been conducted on its phytochemical components or its possible antimicrobial properties. Considering the current problem of antimicrobial multi-resistance of microorganisms, the main objective of this study was to determine the antimicrobial effectiveness of the aqueous extract of Nautilocalyx pallidus (Sprague) “Kᵻtove” against microbial strains from the ATCC collection. For this purpose, a qualitative phytochemical analysis was initially carried out by thin layer chromatography, in order to identify the main compounds responsible for its potential antimicrobial effects, followed by an evaluation of its antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes), Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and a yeast (Candida albicans) using the well diffusion technique. The results of the phytochemical analysis of the aqueous extract of Nautilocalyx pallidus (Sprague) “Kᵻtove” revealed the presence of several bioactive compounds that could be responsible for its therapeutic and antimicrobial properties. Evaluation of antimicrobial properties showed that the pure plant extract did not exhibit activity against Pseudomonas aeruginosa or Escherichia coli, while both the pure extract and its 10% dilution exhibited antibacterial activity against Staphylococcus aureus and Streptococcus pyogenes; furthermore, the 10% extract showed moderate activity against Candida albicans.es_CO
dc.format.extent101es_CO
dc.format.mimetypeapplication/pdfes_CO
dc.language.isoeses_CO
dc.publisherUniversidad de Pamplona - Facultad de Ciencias Básicas.es_CO
dc.subjectAntimicrobiano.es_CO
dc.subjectCromatografía.es_CO
dc.subjectDifusión de pozos.es_CO
dc.subjectFitoquímicos.es_CO
dc.subjectKᵻtove.es_CO
dc.subjectNautilocalyx pallidus (Sprague).es_CO
dc.titleEvaluación de la actividad antimicrobiana de componentes fitoquímicos de un extracto acusoso de la planta medicinal indígena Uitoto Nautilocalyx Pallidus (Sprague) “Kᵻtove” frente a cepas microbianas de colección.es_CO
dc.typehttp://purl.org/coar/resource_type/c_7a1fes_CO
dc.date.accepted2024-
dc.description.editionUniversidad de Pamplona - Facultad de Ciencias Básicas.es_CO
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