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dc.contributor.authorSánchez Aya, Lina Fernanda.-
dc.date.accessioned2026-10-10T23:59:41Z-
dc.date.available2024-
dc.date.available2026-10-10T23:59:41Z-
dc.date.issued2024-
dc.identifier.citationSánchez Aya, L. F. (2024). Contribución de las comunidades microbianas en los procesos de metilación y desmetilación de Mercurio: un acercamiento metagenómico a la problemática de contaminación por mercurio en Colombia. [Trabajo de Grado Pregrado, Universidad de Pamplona]. Repositorio Hulago Universidad de Pamplona. https://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/11653es_CO
dc.identifier.urihttps://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/11653-
dc.descriptionEl mercurio, especialmente en su forma más tóxica, el metilmercurio, es un contaminante ambiental persistente motivado preocupación a nivel global debido a su alta toxicidad y capacidad de bioacumulación en ecosistemas acuáticos y terrestres; en donde procesos antropogénicos como la minería ilegal ha intensificado este problema, siendo una fuente importante de liberación de mercurio al ambiente mundialmente y en particular en Colombia, donde en los últimos años se ha datado un aumento en las emisiones de dicho contaminante. Los microorganismos juegan un papel crucial en la biogeoquímica del mercurio, principalmente a través de operones como hgc y mer, los cuales son fundamentales en los procesos de metilación y desmetilación del mercurio. En este estudio, se procesaron lecturas crudas de metagenomas ambientales de 74 bioproyectos de 9 localidades de Colombia mediante análisis metagenómico, obteniendo como resultado 175 MAGs, dentro de los cuales, se identificaron 16 MAGs como candidatos potenciales para la biotransformación del mercurio, entre ellos, uno corresponde al operón mer, mientras que los restantes 15 están asociados al operón hgc.es_CO
dc.description.abstractMercury, especially in its most toxic form, methylmercury, is a persistent environmental pollutant that has raised global concern due to its high toxicity and ability to bioaccumulate in aquatic and terrestrial ecosystems. Illegal mining has exacerbated this problem, being a significant source of mercury release into the environment worldwide, particularly in Colombia, where an increase in emissions of this pollutant has been observed in recent years. Microorganisms play a crucial role in the biogeochemistry of mercury, primarily through operons such as hgc and mer, which are essential in the processes of methylation and demethylation of mercury. In this study, raw metagenomic reads from 74 bioprojects in 9 locations across Colombia were processed through metagenomic analysis, resulting in 175 MAGs. Among these, 16 MAGs were identified as potential candidates for mercury biotransformation, with one corresponding to the mer operon and the remaining 15 associated with the hgc operon.es_CO
dc.format.extent78es_CO
dc.format.mimetypeapplication/pdfes_CO
dc.language.isoeses_CO
dc.publisherUniversidad de Pamplona - Facultad de Ciencias Básicas.es_CO
dc.subjectLa autora no proporciona la información sobre este ítem.es_CO
dc.titleContribución de las comunidades microbianas en los procesos de metilación y desmetilación de Mercurio: un acercamiento metagenómico a la problemática de contaminación por mercurio en Colombia.es_CO
dc.typehttp://purl.org/coar/resource_type/c_7a1fes_CO
dc.date.accepted2024-
dc.description.editionUniversidad de Pamplona - Facultad de Ciencias Básicas.es_CO
dc.relation.referencesAchá, D., Hintelmann, H., & Yee, J. (2011). Importance of sulfate reducing bacteria in mercury methylation and demethylation in periphyton from Bolivian Amazon region. Chemosphere, 82(6), 911-916.es_CO
dc.relation.referencesAllison, S. D., y Martiny, J. B. (2008). Resistance, resilience, and redundancy in microbial communities. Proceedings of the National Academy of Sciences of the United States of America, 105(1), 11512–11519. https://doi.org/10.1073/pnas.0801925105es_CO
dc.relation.referencesAlbertsen, M., Hugenholtz, P., Skarshewski, A., Nielsen, K. L., Tyson, G. W., & Nielsen, P. H. (2013). Genome sequences of rare, uncultured bacteria obtained by differential coverage binning of multiple metagenomes. Nature Biotechnology, 31(6), 533- 538.es_CO
dc.relation.referencesBae, H. S., Dierberg, F. E., y Ogram, A. (2014). Syntrophs dominate sequences associated with the mercury methylation-related gene hgcA in the water conservation areas of the Florida Everglades. Applied and Environmental Microbiology, 80(20), 6517–6526. doi: 10.1128/AEM.01666-14es_CO
dc.relation.referencesBarkay, T., Miller, S. M., y Summers, A. O. (2003). Bacterial mercury resistance from atoms to ecosystems. FEMS Microbioly Reviews. 27, 355-384. doi: 10.1016/s0168- 6445(03)00046-9es_CO
dc.relation.referencesBarkay, T., y Wagner-Döbler, I. (2005). Microbial transformations of mercury: Potentials, challenges, and achievements in controlling mercury toxicity in the environment. Advances in Applied Microbiology, 57, 1–52. https://doi.org/10.1016/S0065- 2164(05)57001-1es_CO
dc.relation.referencesBravo AG, Peura S, Buck M, Ahmed O, Mateos-Rivera A, Ortega SH, Schaefer JK, Bouchet S, Tolu J, Bjorn E, Bertilsson S (2018a) Methanogens and iron-reducing bacteria: the overlooked members of mercury-methylating microbial communities in Boreal Lakes. Appl Environ Microb 84(23):e01774– e01718. https://doi.org/10.1128/aem.01774-18es_CO
dc.relation.referencesBeckers, F., Mothes, S., Abrigata, J., Zhao, J., Gao, Y., y Rinklebe, J. (2019). Mobilization of mercury species under dynamic laboratory redox conditions in a contaminated floodplain soil as affected by biochar and sugar beet factory lime. Science of The Total Environment, 672, 604–617. doi: 10.1016/j.scitotenv.2019.03.401). Environmental Science & Technology, 35(1), 127–132. doi:10.1021/es001415nes_CO
dc.relation.referencesBedoya K, Niño J, Acero J, Jaimes-Prada R, Cabarcas F y Alzate JF (2021) El análisis metagenómico del agua de yacimientos de petróleo neotropicales tratada con biocidas revela la microdiversidad de la especie termófila Tepidiphilus . Front. Microbiol. 12:741555. doi: 10.3389/fmicb.2021.741555es_CO
dc.relation.referencesBowers, R. M., Kyrpides, N. C., Stepanauskas, R., Harmon-Smith, M., Doud, D., Reddy, T. B. K., et al. (2017). Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of Bacteria and Archaea. Nat. Biotechnol. 35, 725–731. doi: 10.1038/nbt.3893es_CO
dc.relation.referencesBoyd, E. S., y Barkay, T. (2012). The mercury resistance operon: From an origin in a geothermal environment to an efficient detoxification machine. Frontiers in Microbiology, 3. https://doi.org/10.3389/fmicb.2012.00349es_CO
dc.relation.referencesBridou, R., Monperrus, M., Gonzalez, P. R., Guyoneaud, R., y Amouroux, D. (2011). Simultaneous determination of mercury methylation and demethylation capacities of various sulfate-reducing bacteria using species-specific isotopic tracers. Environmental Toxicology and Chemistry, 30, 337-344. doi: 10.1002/etc.395es_CO
dc.relation.referencesCapo, E., Peterson, B. D., Kim, M., Jones, D. S., Acinas, S. G., Amyot, M., ... & Gionfriddo, C. M. (2023). A consensus protocol for the recovery of mercury methylation genes from metagenomes. Molecular Ecology Resources, 23(1), 190-204.es_CO
dc.relation.referencesChaumeil, P. A., Mussig, A. J., Hugenholtz, P., & Parks, D. H. (2022). GTDB-Tk v2: memory friendly classification with the genome taxonomy database. Bioinformatics (Oxford, England), 38(23), 5315–5316. https://doi.org/10.1093/bioinformatics/btac672es_CO
dc.relation.referencesChoi S.-C. and Bartha R. Environmental factors affecting mercury methylation in estuarine sediments. Bull. Environ. Contam. Toxicol. 53 1994 805 -812es_CO
dc.relation.referencesCompeau, G. C., Bartha, R. (1985). Sulfate-reducing bacteria: main mercury methylators inanoxic estuarine sediments.Applied and Environmental, 50, 498–502.es_CO
dc.relation.referencesDavila Aleman, F. D., Bautista, M. A., McCalder, J., Jobin, K., Murphy, S. M., Else, B., & Hubert, C. R. (2024). Novel oil-associated bacteria in Arctic seawater exposed to different nutrient biostimulation regimes. bioRxiv. https://doi.org/10.1101/2024.03.00.485743es_CO
dc.relation.referencesDietrich, G. J., Dietrich, M., Kowalski, R. K., Dobosz, S., Karol, H. y Demianowicz, W. (2010). Exposure of rainbow trout milt to mercury and cadmium alters sperm motility parameters and reproductive success. Aquatic Toxicology, 97, 277–284. doi: 10.1016/j.aquatox.2009.12.010es_CO
dc.relation.referencesDorrepaal, E., Toet, S., van Logtestijn, R. S. P., Swart, E., van de Weg, M. J. y Callaghan, T.V. (2009). Carbon respiration from subsurface peat accelerated by climate warming in the subarctic. Nature, 460, 616–619. doi: 10.1038/nature08216es_CO
dc.relation.referencesEddy, S. R. (2020). HMMER user’s guide: biological sequence analysis using profile hidden Markov models. Howard Hughes Medical Institute.es_CO
dc.relation.referencesEmms, D. M., y Kelly, S. (2019). OrthoFinder: inferencia de ortología filogenética para genómica comparada. Biología del genoma, 20 , 1-14.es_CO
dc.relation.referencesEnamorado, G., Montoya, J. T., & Negrete, J. M. (2022). Metales pesados (Hg, As, Cd, Zn, Pb, Cu, Mn) en un trayecto del río Cauca impactado por la minería de oro. Revista EIA, 19(37), 37005-pp.es_CO
dc.relation.referencesFinn, R. D., Bateman, A., Clements, J., Coggill, P., Eberhardt, R. Y., Eddy, S. R., ... & Punta, M. (2014). Pfam: the protein families database. Nucleic acids research, 42(D1), D222-D230.es_CO
dc.relation.references] García-López, M., Meier-Kolthoff, J.P., Tindall, B.J., Gronow, S., Woyke, T., Kyrpides, N.C., Hahnke, R.L., Göker, M. (2019) Analysis of 1,000 type-strain genomes improves taxonomic classification of Bacteroidetes. Front. Microbiol. 10, 2083, http://dx.doi.org/10.3389/fmicb.2019.02083.es_CO
dc.relation.referencesGaioli, M., Amoedo, D., & González, D. (2012). Impacto del mercurio sobre la salud humana y el ambiente. Archivos argentinos de pediatría, 110(3), 259-264.es_CO
dc.relation.referencesGilmour, C. C., Elias, D. A., Kucken, A. M., Brown, S. D., Palumbo, A. V. y Schadt, C. W. (2011). Sulfate-reducing bacterium Desulfovibrio desulfuricans ND132 as a model for understanding bacterial mercury methylation. Applied and Environmental Microbiology, 77, 3938-3951. doi: 10.1128/aem.02993-10es_CO
dc.relation.referencesGilmour, C. C., Podar, M., Bullock, A. L., Graham, A. M., Brown, S. D., Somenahally, A. C., Johs, A., Hurt, R. A., Bailey, K. L., Elias, D. A. (2013). Mercury methylation by novel microorganisms from new environments. Environmental Science Technology, 47, 11810-11820. doi: 10.1021/es403075t.es_CO
dc.relation.referencesGionfriddo C. M., Wymore A. M., Jones D. S., Wilpiszeski R. L., Lynes M. M., Christensen G. A. (2020). An improved hgcAB primer set and direct high-throughput sequencing expand Hg-methylator diversity in nature. Front. Microbiol. 11. doi: 10.3389/fmicb.2020.541554es_CO
dc.relation.referencesGionfriddo, C. M., Stott, M. B., Power, J. F., Ogorek, J. M., Krabbenhoft, D. P., Wick, R.,Holt, K., Chen, L. X., Thomas, B. C., Banfield, J. F., & Moreau, J. W. (2020). Genome-Resolved Metagenomics and Detailed Geochemical Speciation Analyses Yield New Insights into Microbial Mercury Cycling in Geothermal Springs. Applied and Environmental Microbiology, 86(15). https://doi.org/10.1128/AEM.00176-20es_CO
dc.relation.referencesHaft, D. H., Loftus, B. J., Richardson, D. L., Yang, F., Eisen, J. A., Paulsen, I. T., & White, O. (2001). TIGRFAMs: a protein family resource for the functional identification of proteins. Nucleic acids research, 29(1), 41-43.es_CO
dc.relation.referencesHamelin S, Amyot M, Barkay T, Wang YP, Planas D (2011) Methanogens: principal methylators of mercury in Lake Periphyton. Environ Sci Technol 45(18):7693– 7700. https://doi.org/10. 1021/es2010072es_CO
dc.relation.referencesHelbig, M., Waddington, J. M., Alekseychik, P., Amiro, B. D., Aurela, M. y Barr, A. G. (2020). Increasing contribution of peatlands to boreal evapotranspiration in a warming climate. Nature Climate Change, 10, 555–560. doi: 10.1038/s41558-020-0763-7es_CO
dc.relation.referencesHuson, D. H., Richter, D. C., Mitra, S., Auch, A. F., & Schuster, S. C. (2009). Methods for comparative metagenomics. BMC bioinformatics, 10, 1-10.es_CO
dc.relation.referencesHyatt, D., Chen, G. L., LoCascio, P. F., Land, M. L., Larimer, F. W., & Hauser, L. J. (2010). Prodigal: prokaryotic gene recognition and translation initiation site identification. BMC bioinformatics, 11, 1-11.es_CO
dc.relation.referencesIdrovo, Á., Manotas, L., Villamil, G., Ortíz, J., Silva, E., Romero, S., & Azcárate, C. (2001). Niveles de mercurio y percepción del riesgo en una población minera aurifera del Guainía (Orinoquía Colombiana). Biómedica. Recuperado de: http://www.scielo.org.pe/scielo.phppid=S172859172010000400016&script=sci_arttext&t lng=ees_CO
dc.relation.referencesJaffe, R., McKnight, D., Maie, N., Cory, R. y McDowell, W. H. (2008). Spatial and temporal variations in DOM composition in ecosystems: The importance of long-term monitoring of optical properties. Journal of Geophysical Research, 113, 1-15. doi: 10.1029/2008JG000683es_CO
dc.relation.referencesJi, X., Liu, C., Zhang, M., Yin, Y., y Pan, G. (2020). Mitigation of methylmercury production in eutrophic waters by interfacial oxygen nanobubbles. Water Research, 173. doi: 10.1016/j.watres.2020.115563es_CO
dc.relation.referencesJohnson, N. W., Mitchell, C. P. J., Engstrom, D. R., Bailey, L. T., Coleman Wasik, J. K., y Berndt, M. E. (2016). Methylmercury production in a chronically sulfate-impacted sub-boreal wetland. Environmental Science: Processes & Impacts, 18(6), 725–734. doi: 10.1039/c6em00138fes_CO
dc.relation.referencesJonsson, S., Skyllberg, U., Nilsson, M. B., Westlund, P.-O., Shchukarev, A. y Lundberg, E. (2012). Mercury methylation rates for geochemically relevant HgII species in sediments. Environmental Science & Technology, 46, 11653–11659. doi: 10.1021/es3015327es_CO
dc.relation.referencesKanehisa, M., Furumichi, M., Sato, Y., Kawashima, M., & Ishiguro-Watanabe, M. (2023). KEGG for taxonomy-based analysis of pathways and genomes. Nucleic acids research, 51(D1), D587-D592.es_CO
dc.relation.referencesKim, M., Han, S., Gieskes, J., y Deheyn, D. D. (2011). Importance of organic matter reliability for monomethylmercury production in sulfate-rich marine sediments. Science of The Total Environment, 409(4), 778–784. doi: 10.1016/j.scitotenv.2010.10.050es_CO
dc.relation.referencesKodama, Y., Shumway, M., Leinonen, R., & International Nucleotide Sequence Database Collaboration (2012). The Sequence Read Archive: explosive growth of sequencing data. Nucleic acids research, 40(Database issue), D54–D56. https://doi.org/10.1093/nar/gkr854es_CO
dc.relation.referencesKrabbenhoft, D. P., y Sunderland, E. M. (2013). Global change and mercury. Science, 341(6153), 1457–1458. doi: 10.1126/science.1242838es_CO
dc.relation.referencesKrueger, F. (2015). Trim Galore: A wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for RRBS data. Babraham Institute.es_CO
dc.relation.referencesKumari, S., Amit, Jamwal, R., Mishra, N., y Singh, D. K. (2020). Recent Developments in Environmental Mercury Bioremediation and its Toxicity: A Review. Environmental Nanotechnology, Monitoring & Management, 13. https://doi.org/10.1016/j.enmm.2020.100283es_CO
dc.relation.referencesLeinonen, R., Sugawara, H., Shumway, M., & International Nucleotide Sequence Database Collaboration. (2011). The sequence read archive. Nucleic acids research, 39(suppl_1), D19-D21. https://doi.org/10.1093/nar/gkq1019es_CO
dc.relation.referencesLi, Y., y Cai, Y. (2023). Progress in the study of mercury methylation and demethylation in aquatic environments. Chinese Science Bulletin, 58, 177–185. doi: 10.1007/s11434- 012-5416-4es_CO
dc.relation.referencesLi, D., Liu, C. M., Luo, R., Sadakane, K., & Lam, T. W. (2015). MEGAHIT: An ultra-fast sin-gle-node solution for large and complex metagenomics assembly via succinct de Bruijn graph. Bioin-formatics, 31(10), 1674-1676. https://doi.org/10.1093/bioinformatics/btv033es_CO
dc.relation.referencesLin, H., Ascher, D. B., Myung, Y., Lamborg, C. H., Hallam, S. J. y Gionfriddo, C. M. (2021). Mercury methylation by metabolically versatile and cosmopolitan marine bacteria. The ISME Journal, 15(6), 1810–1825. doi: 10.1038/s41396-020-00889-4es_CO
dc.relation.referencesLiu, M., Zhang, Q., Maavara, T., Liu, S., Wang, X., y Raymond, P. A. (2021). Rivers as the largest source of mercury to coastal oceans worldwide. Nature Geoscience, 14(9), 672–677. doi: 10.1038/s41561-021-00793-2es_CO
dc.relation.referencesLiu, Y. R., Yu, R. Q., Zheng, Y. M., He, J. Z. (2014). Analysis of the microbial community structure by monitoring an Hg methylation gene (hgcA) in paddy soils along an Hg gradient. Applied and Environmental Microbiology, 80. 2874-2879. doi: 10.1128/AEM.04225-13.es_CO
dc.relation.referencesLu, X., Gu, W., Zhao, L., Farhan Ul Haque, M., DiSpirito, A. A. y Semrau, J. D. (2017). Methylmercury uptake and degradation by methanotrophs. Science Advances, 3(5), e1700041. doi: 10.1126/sciadv.1700041es_CO
dc.relation.referencesLücker, S., Nowka, B., Rattei, T., Spieck, E., Daims, H., & Wagner, M. (2010). A Nitrospira metagenome illuminates the physiology and evolution of globally important nitrite-oxidizing bacteria. Proceedings of the National Academy of Sciences, 107(30), 13479–13484. https://doi.org/10.1073/pnas.1003860107es_CO
dc.relation.referencesMason, R. P., y Fitzgerald, W. F. (1993). The distribution and biogeochemical cycling of mercury in the equatorial Pacific Ocean. Deep Sea Research Part I: Oceanographic Research Papers, 40(9), 1897–1924. doi: 10.1016/0967-0637(93)90037-4es_CO
dc.relation.referencesMartínez, J. A., & Uribe, A. (2015). El Mercurio y la contaminación por actividad extractiva. Revista Ontare, 3(1), 55-76.es_CO
dc.relation.referencesMcDaniel, E. A., Peterson, B. D., Stevens, S. L. R., Tran, P. Q., Anantharaman, K., and McMahon, K. D. (2020). Expanded phylogenetic diversity and metabolic flexibility of mercury-methylating microorganisms. mSystems 5: e299-20. doi: 10.1128/mSystems.00299-20es_CO
dc.relation.referencesMcMurdie, P. J., & Holmes, S. (2013). phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. PloS one, 8(4), e61217.es_CO
dc.relation.referencesMinamata Disease Research Group. (1966). Minamata Disease: Studies About Methyl- Mercury Poisoning (in Japanese) (Kumamoto, Japan: Kumamoto University School of Medicine).es_CO
dc.relation.referencesMolina, C. F., Arango, C. M., & Sepúlveda, H. (2018). Contaminación por mercurio de leche materna de madres lactantes de municipios de Antioquia con explotación minera de oro. Biomédica, 38, 19-29.es_CO
dc.relation.referencesNavarro, W. M., Ccarita, W. R. I., Paredes, D. W. D. la C., Sacachipana, N. Z., Sucaticona, R. S., Coaquira, D. M. (2019). Adsorción de metales pesados de aguas residuales de la mina Lunar de Oro con carbón activado de lenteja de agua (Lemna gibba L.). ÑAWPARISUM – Revista de Investigación Científica, 1(2), 13 20.https://unaj.edu.pe/revista/index.php/vpin/article/view/27/12es_CO
dc.relation.referencesNavas-Cáceres, OD, Parada, M. y Zafra, G. Desarrollo de un consorcio bacteriano altamente tolerante a la biodegradación de asfaltenos en suelos. Environ Sci Pollut Res 30, 123439–123451 (2023). https://doi.org/10.1007/s11356-023-30682-7es_CO
dc.relation.referencesOlivero, J., Johnson, B., Mendoza, C., Paz, R., y Olivero, R. (2004). Mercury in the aquaticenvironment of The Village of Caimito at The Mojana Region, North of Colombia. Water, Air, & Soil Pollution, 159, 409-420. https://doi.org/10.1023/B:WATE.0000049162.54404.76es_CO
dc.relation.referencesOlivero, J., y Solano, B. (1998). Mercury in environmental samples from a waterbody contaminated by gold mining in Colombia, South America. Science of The Total Environment, 217, 83-89. Doi:10.1016/s0048-9697(98)00175-2es_CO
dc.relation.referencesOsborn, A. M., Bruce, K. D., Strike, P., & Ritchie, D. A. (1997). Distribution, diversity, and evolution of the bacterial mercury resistance (mer) operon. FEMS microbiology reviews, 19(4), 239-262.es_CO
dc.relation.referencesParks, J. M., Johs, A., Podar, M., Bridou, R., Hurt, R. A. y Smith, S. D. (2013). The genetic basis for bacterial mercury methylation. Science, 339(6125), 1332–1335. doi: 10.1126/science.1230667es_CO
dc.relation.referencesParks, D. H., Chuvochina, M., Rinke, C., Mussig, A. J., Chaumeil, P. A., & Hugenholtz, P. (2022). GTDB: an ongoing census of bacterial and archaeal diversity through a phylogenetically consistent, rank normalized and complete genome-based taxonomy. Nucleic acids research, 50(D1), D785-D794. https://doi.org/10.1093/nar/gkab776es_CO
dc.relation.referencesParks, D. H., Imelfort, M., Skennerton, C. T., Hugenholtz, P., & Tyson, G. W. (2015). CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes. Genome Research, 25(7), 1043-1055.es_CO
dc.relation.referencesPatro, R., Duggal, G. y Kingsford, C. (2015). Salmón: cuantificación precisa, versátil y ultrarrápida a partir de datos de secuenciación de ARN mediante alineación ligera. BioRxiv , 10, 021592.es_CO
dc.relation.referencesPardo, A., & Rangel-Ch, J. O. (2014). Mamíferos de la Orinoquia. In J. O. Rangel- Ch (Ed.), Colombia Diversidad Biótica XIV (pp. 751-784). Bogotá, Colombia: Instituto de Ciencias Naturales, Facultad de Ciencias, Universidad Nacional de Colombia.es_CO
dc.relation.referencesPerez, C., Qi, W., Vikram, S., Frossard, A., Makhalanyane, T., y Cowan, D. (2021). Shotgun metagenomics reveals distinct functional diversity and metabolic capabilities between 12,000-year-old permafrost and active layers on Muot da Barba Peider (Swiss Alps). Microbial Genomics, 7(2). https://doi.org/10.1099/mgen.0.000558es_CO
dc.relation.referencesPodar, M.; Gilmour, C. C.; Brandt, C. C.; Soren, A.; Brown, S. D.; Crable, B. R.; Palumbo, A. V.; Somenahally, A. C. y Elias, D. A. (2015). Global prevalence and distribution of genes and microorganisms involved in mercury methylation. Science Advances, 1(9). doi: 10.1126/sciadv.1500675.es_CO
dc.relation.referencesPodosokorskaya, O. A., Kochetkova, T. V., Novikov, A. A., Toshchakov, S. V., Elcheninov, A. G., & Kublanov, I. V. (2020). Tenuifilum thalassicum gen. nov., sp. nov., a novel moderate thermophilic anaerobic bacterium from a Kunashir Island shallow hot spring representing a new family Tenuifilaceae fam. nov. in the class Bacteroidia. Systematic and Applied Microbiology, 126126. doi:10.1016/j.syapm.2020.126126es_CO
dc.relation.referencesProcuraduría General de la Nación. (2023). Colombia el mayor emisor de mercurio per cápita en el mundo. Boletín 95. https://www.procuraduria.gov.co/Pages/colombiamayor- emisor-de-mercurio-por-persona-en-el-mundo.aspxes_CO
dc.relation.referencesRamírez, A. V. (2008, March). Intoxicación ocupacional por mercurio. In Anales de la Facultad de Medicina (Vol. 69, No. 1, pp. 46-51). UNMSM. Facultad de Medicinaes_CO
dc.relation.referencesR Core Team. (2019). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing.es_CO
dc.relation.referencesRincón-Tomás, B., Lanzén, A., Sánchez, P., Estupiñán, M., Sanz-Sáez, I., Bilbao, M. E., ... & Alonso-Sáez, L. (2024). Revisiting the mercury cycle in marine sediments: A potential multifaceted role for Desulfobacterota. Journal of Hazardous Materials, 465, 133120.es_CO
dc.relation.referencesSánchez, D., & Cañón, J. (2010). Análisis documental del efecto de vertimiento domésticos y mineros en la calidad del agua del río Condoto (Chocó, Colombia). Redalyc. Recuperado de: http://www.redalyc.org/html/1694/169419996009es_CO
dc.relation.referencesSchaefer, J. K., Kronberg, R. M., Morel, F. M. M., y Skyllberg, U. (2014). Detection of a key Hg methylation gene, hgcA, in wetland soils. Environmental Microbiology Reports, 6(5), 441–447. https://doi.org/10.1111/1758-2229.12136es_CO
dc.relation.referencesSeemann, T. (2014). Prokka: rapid prokaryotic genome annotation. Bioinformatics, 30(14), 2068-2069.es_CO
dc.relation.referencesSostenible, S., & Latinoamérica, M. (2016). Veneno en la Sangre. Recuperado de: http://sostenibilidad. semana. com/medio-ambiente/multimedia/mercurio-en-colombiaveneno- en-la-sangre/37266.es_CO
dc.relation.referencesSueoka, N. (1962). On the genetic basis of variation and heterogeneity of DNA base composition. Proceedings of the National Academy of Sciences of the United States of America, 48(5), 582-592.es_CO
dc.relation.referencesTarazona. D. (28 de noviembre de 2023). Minería ilegal aumentó un 8 % durante el año 2022 en Colombia. MONGABAY. https://es.mongabay.com/2023/11/mineria-ilegalaumento- en-colombia-informe/es_CO
dc.relation.referencesUritskiy, G. V., DiRuggiero, J., & Taylor, J. (2018). MetaWRAP-a flexible pipeline for genome-resolved metagenomic data analysis. Microbiome, 6(1), 158. https://doi.org/10.1186/s40168-018-0541-1es_CO
dc.relation.referencesVillar, E., Cabrol, L., y Heimbürger-Boavida, L. E. (2020). Widespread microbial mercury methylation genes in the global ocean. Environmental Microbiology Reports, 12(3), 277–287. doi: 10.1111/1758-2229.12829es_CO
dc.relation.referencesWickham, H., Averick, M., Bryan, J., Chang, W., McGowan, L. D. A., François, R., ... & Yutani, H. (2019). Welcome to the Tidyverse. Journal of open-source software, 4(43), 1686.es_CO
dc.relation.referencesYang Y, Pan J, Zhou Z, Wu J, Liu Y, Lin JG, et al. Complex microbial nitrogencycling networks in three distinct anammox‐inoculated wastewater treatment systems. Water Res. 2020; 168:115142.es_CO
dc.relation.referencesYu, R. Q.; Reinfelder, J. R., Hines, M. E. y Barkay, T. (2013). Mercury methylation by methanogen Methanospirillum hungatei. Applied and Environmental, 79, 6325-6330.es_CO
dc.relation.referencesZhang, S.-P., Wang, Q., Quan, S.-W., Yu, X.-Q., Wang, Y., Guo, D.-D., et al. (2020). Sistema toxina-antitoxina tipo II en bacterias: activación, función y modo de acción. Biophys. Rep. 6, 68–79. doi: 10.1007/s00284-020-01983-8es_CO
dc.relation.referencesZhang L, Liu X, Sampath S, Sidelinger W, Wang Y, Krabbenhoft D, Barkay T, Schaefer J, Hines M (2015) Mercury methylation by syntrophs and methanogens in peatlands. In: Abstracts of Papers of the American Chemical Society, vol 250es_CO
dc.relation.referencesZhang, L., Liang, X., Wang, Q., Zhang, Y., Yin, X. y Lu, X. (2021). Isotope exchange between mercuric [Hg (II)] chloride and Hg (II) bound to minerals and thiolate ligands: Implications for enriched isotope tracer studies. Geochimica et Cosmochimica Acta, 292, 468–481. doi: 10.1016/j.gca.2020.10.013es_CO
dc.relation.referencesZhang, Y., Song, Z., Huang, S., Zhang, P., Peng, Y. y Wu, P. (2021). Global health effects of future atmospheric mercury emissions. Nature Communications, 12, 1–10.es_CO
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