Verificación de la efectividad de los sanitizantes ambientales utilizados en la rotación de desinfectantes del laboratorio de farmacología Vegetal-Labfarve.

Abstract

In this study, the effectiveness of Sodium Hypochlorite, glutaraldehyde, glutaraldehyde + formaldehyde and alcohol was verified in processing environments of the LABFARVE plant pharmacology laboratory. For this, the recommendations of USP <1072>, 2023 and USP <1227>, 2023 and the AOAC method were followed, evaluating the disinfectants with native strains from the production plant and ATCC strains of Ps. aeruginosa, E. coli, S. aureus, Bacillus spizizenii, C. albicans, As. brasiliensis. To obtain the native strains, samples were taken from the environments of the phytotherapeutic, cosmetic and master formula plants by means of the plate sedimentation method, where they were isolated and subsequently identified in an external laboratory. The isolated native microorganisms corresponded to Bacillus subtilis and Penicillium marneffei; these native strains showed greater resistance to the disinfectant treatments tested, highlighting that for 1% Sodium Hypochlorite, 2% Glutaraldehyde, 2% Glutaraldehyde + Formaldehyde and 96% Ethanol, a longer time was required for their elimination compared to the ATCC strains. The results of this study highlight the need to customize disinfection protocols according to the characteristics of the native strains present in industrial processing environments.