Determinación del origen étnico de la población mestiza colombiana mediante los sistemas HLA-A, B Y DRB1.

Abstract

This research aims to establish the gene pool of the Colombian mestizo population by comparing the allele and haplotype frequencies of HLA-A, B, DRB1 of Caucasian ethnic groups, Native American, Asian and African system with ours. An observational study was conducted quantitative through data collection obtained in the www.alellefrequencies.net page in Colombian literature, gathering the ethnic populations and calculating an average of allele frequencies for each locus, likewise haplotype frequencies are calculated from these data cladograms be built and principal component analysis will, performing statistical analyzes through GENECLASS version 2.0 software. This methodology allows us to approach to assess the degree of kinship and miscegenation of Colombian mestizo population with different ethnic groups documentadamente participated in their training.