• Repositorio Institucional Universidad de Pamplona
  • Trabajos de pregrado y especialización
  • Facultad de Ciencias Agrarias
  • Medicina Veterinaria
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    dc.contributor.authorParra Jaimes, Julian David.-
    dc.date.accessioned2022-05-13T02:57:13Z-
    dc.date.available2018-09-15-
    dc.date.available2022-05-13T02:57:13Z-
    dc.date.issued2018-
    dc.identifier.citationParra Jaimes, J. D. (2018). Linfoma linfoblástico difuso multicéntrico de alto grado en un canino [Trabajo de Grado Pregrado, Universidad de Pamplona]. Repositorio Hulago Universidad de Pamplona. http://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/736es_CO
    dc.identifier.urihttp://repositoriodspace.unipamplona.edu.co/jspui/handle/20.500.12744/736-
    dc.descriptionSe presentó el caso clínico de un canino con linfoma linfoblástico difuso multicéntrico de alto grado, diagnosticado gracias al examen físico, estudios hematológicos, citológicos e histopatológicos y ultrasonográficos realizados en la Clínica Veterinaria de Pequeños Animales MascoVet Cúcuta – Colombia. El paciente ingresó a consulta por aumento de tamaño y dolor a la palpación en la región submandibular, escapular y a nivel caudal de los miembros posteriores relacionados a la ubicación de los linfonodos. Se le realizó examen clínico, cuadros hematológicos, bioquímicas sanguíneas, ultrasonografía, citología e histopatología. Los hallazgos más relevantes fueron linfadenomegalia submandibular, pre-escapular, poplítea superficial e iliaca media bilateral, esplenomegalia, mediante palpación y ultrasonografía. Bicitopenia por leucopenia (neutrofilia y linfopenia) y trombocitopenia, hipoproteinemia mediante hematología. Linfoma mediante citología. Por histopatología, tumor maligno de células redondas: linfoma linfoblástico difuso de alto grado. Se trató con el protocolo CHOP de 19 semanas de la Universidad de Wisconsin-Madison para perros. El paciente presentó respuesta completa a partir de la primera semana de CHOP y se mantuvo estable hasta la cuarta semana, donde posterior a la aplicación de Doxorrubicina y baja en la posología de Prednisolona el paciente se desestabilizó manifestando vómitos frecuentes y decaimiento, signos que llevaron al propietario a desistir de la quimioterapia.es_CO
    dc.description.abstractThe clinical case of a canine with high-grade multicentric diffuse lymphoblastic lymphoma is presented, diagnosed through physical examination, hematological, cytological and histopathological and ultrasonographic studies carried out at the Veterinary Clinic of Small Animals MascoVet, Cúcuta - Colombia. The patient was admitted due to enlargement and pain on palpation in the submandibular, scapular region and caudal level of the posterior limbs compatible with the location of the lymph nodes. He underwent clinical examination, hematological, blood biochemistry, ultrasonography, cytology and histopathology. The most relevant findings were submandibular lymphadenomegaly, pre-scapular, superficial popliteal and bilateral middle iliac, splenomegaly, by palpation and ultrasonography. Bicitopenia due to leukopenia (neutrophilia and lymphopenia) and thrombocytopenia, hypoproteinemia by hematology. Lymphoma by cytology. By histopathology, malignant tumor of Round cells: high- grade diffuse lymphoblastic lymphoma. It was treated with the 19-week CHOP protocol from the University of Wisconsin-Madison for dogs. The patient presented a complete response of the first week of CHOP and remained stable until the fourth week, where after the application of Doxorubicin and low in the dose of Prednisolone the patient was destabilized, manifesting frequent vomiting and decay, signs that led to the owner to desist from chemotherapy.es_CO
    dc.format.extent113es_CO
    dc.format.mimetypeapplication/pdfes_CO
    dc.language.isoeses_CO
    dc.publisherUniversidad de Pamplona – Facultad de Ciencias Agrarias.es_CO
    dc.subjectLinfoma.es_CO
    dc.subjectLinfadenomegalia.es_CO
    dc.subjectUltrasonografía.es_CO
    dc.subjectItología.es_CO
    dc.subjectHistopatología.es_CO
    dc.subjectCHOP.es_CO
    dc.titleLinfoma linfoblástico difuso multicéntrico de alto grado en un canino.es_CO
    dc.typehttp://purl.org/coar/resource_type/c_7a1fes_CO
    dc.date.accepted2018-06-15-
    dc.relation.referencesArdila M.; Cala F.; Vargas G.; Arcila H.; Castellanos V. (2007, 1 de mayo). Reporte de casos clínicos con Hepatozoon canis en el Centro Médico Quirúrgico Veterinario de la Universidad Cooperativa de Colombia. Redvet. Recuperado de http://www.veterinaria. org/revistas/redvet/n050507/050705.pdfes_CO
    dc.relation.referencesArgyle, D., Brearley, M., & Turek, M. (2008). Decision Making in Small Animal Oncology. Ames, Iowa: Wiley-Blackwell.es_CO
    dc.relation.referencesBauer NB, Zervos D, Moritz A. (2007). Argyrophilic nucleolar organizing regions and Ki67 equally reflect proliferation in fine needle aspirates of normal, hyperplastic, inflamed and neoplastic canine lymph nodes (n = 101). J Vet Intern Med, 21(5), 928–935. doi: 10.1111/ j.1939-1676.2007.tb03045.xes_CO
    dc.relation.referencesBlackwood L, German AJ, Stell AJ and O´Neil T. (2004). Multicentric lymphoma in a dog afer cyclosporine therapy. J Small Anim Pract, 45(5), 259–262. doi: 10.1111/j.1748-5827. 2004.tb00233.xes_CO
    dc.relation.referencesBlackwood L, Sullivan M, Lawson H. (1997). Radiographic abnormalities in canine multicentric lymphoma: A review of 84 cases. J Small Anim Pract 38(2), 62–69. doi: 10.1111/j.1748- 5827.1997.tb02989.xes_CO
    dc.relation.referencesBooth, N.H. (1988). Drugs Acting on the Central Nervous System. In NH Booth and LE McDonald (6 Ed.), Veterinary Pharmacology and Therapeutics (pp. 153). Ames, Iowa State University: Wiley-Blackwell.es_CO
    dc.relation.referencesBreen M & Modiano JF. (2008). Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans man and his best friend share more than companionship. Chromosome Res, 16(1), 145–154. doi: 10.1007/s10577-007-1212-4es_CO
    dc.relation.referencesBurnett RC, Vernau W, Modiano JF, Olver S, Moore P and Avery A. (2003). Diagnosis of canine lymphoid neoplasia using clonal rearrangements of antigen receptor genes. Vet Pathol 40(1), 32–41. doi: 10.1354 / vp.40-1-32es_CO
    dc.relation.referencesCouto, C.G. (2005). Medicina interna de pequeños animales. Madrid: Elsevier España.es_CO
    dc.relation.referencesCouto, C.G. (2015). Linfoma. In Nelson, R.W.; Couto, C.G. (5 Ed.), Medicina interna de pequenos animais (pp. 1160-1174). Rio de Janeiro: Elsevier.es_CO
    dc.relation.referencesCrabtree AC, Spangler E, Beard D, Smith A. (2010). Diagnostic accuracy of gray-scale ultrasonography for the detection of hepatic and splenic lymphoma in dogs, Vet Radiol Ultrasound 51(6), 661–664. doi: 10.1111/j.1740-8261.2010.01725.xes_CO
    dc.relation.referencesDavid M., Pinkerton M., and Young K. (2013). Hematopoietic tumors: canine lymphoma and lymphoid leukemias. In Withrow, S., Vail, D., & Page, R. (5 Ed.), Withrow & MacEwen's small animal clinical oncology (pp. 608-627). St. Louis, Mo.: Elsevier/Saunders.es_CO
    dc.relation.referencesDevitt JJ, Maranon DG, Ehrhart EJ, Bachand A, Lana S and LaRue S. (2009). Correlations between numerical chromosomal aberrations in the tumor and peripheral blood in canine lymphoma. Cytogenet Genome Res, 124(1), 12–18. doi: 10.1159/000200083es_CO
    dc.relation.referencesDickinson, R. M. (2008). Canine lymphosarcoma: Overcoming diagnostic obstacles and introduction to the latest diagnostic techniques. The Canadian Veterinary Journal, 49(3), 305-308. Recuperado de https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249731/es_CO
    dc.relation.referencesDubey, J. y C. Greene (2006). Enteric coccidiosis. In C Greene (3 Ed.), Infectious Diseases of the Dogs and Cat (pp. 775-784). St. Louis, Missouri: Elsevier.es_CO
    dc.relation.referencesFighera, R.A, Mello T, Rodrigues A and Lombardo C. (2006). Aspectos clinicopatológicos de 43 casos de linfoma em cães. MEDVEP – Revista Científica de Medicina Veterinária – Pequenos Animais e Animais de Estimação, 4(12), 139-146. Recuperado de http://www.rafaelfighera.com.br/wp-content/uploads/2014/06/rafaelfighera_linfoma-em- caes.pdfes_CO
    dc.relation.referencesFoil, C. (September of 2003). Update on treating scabies and cheyletiella. In The Dr. Jack Walther 85th Annual Western Veterinary Conference. Mandalay Bay Convention Center, Las Vegas, NV. Recuperado de https://s3-us-west-2.amazonaws.com/wvc- organization/projects/Marketing/Archives+/2013-wvc-scientific-program-exhibit-hall- guide.pdfes_CO
    dc.relation.referencesFoster AP, Sturgess CP, Gould DJ, Iwasakit T and Day MJ. (2000). Pemphigus foliaceus in association with systemic lupus erythematosus and subsequent lymphoma in a cocker spaniel. J Small Anim Pract, 41(6), 266–270. doi: 10.1111/j.1748-5827.2000.tb03938.xes_CO
    dc.relation.referencesGibson D, Aubert I, Woods JP, Abrams-Ogg A, Kruth S, Madera RD and Bienzle D. (2004). Flow cytometric immunophenotype of canine lymph node aspirates. J Vet Intern Med, 18(5), 710–717. doi: 10.1111/j.1939-1676.2004.tb02610.xes_CO
    dc.relation.referencesGreene, C. (2006a). Gastrointestinal and Intraabdominal Infections. In C Greene (3 Ed.), Infectious Diseases of the Dog and Cat (pp. 883-912). St. Louis, Missouri: Elsevier.es_CO
    dc.relation.referencesGreene, C. (2006b). Appendix 8: Antimicrobial Drug Formulary. In C Greene (3 Ed.), Infectious Disease of the Dog and Cat (pp: 1186–1333). St. Louis, Missouri: Elsevier.es_CO
    dc.relation.referencesGrindem CB, Breitschwadt, EB, Corbett WT, Page RL and Jans HE. (1994). Trombocytopenia associated with neoplasia in dogs. J Vet Intern Med, 8(6), 400–405. doi: 10.1111/j.1939- 1676.1994. tb03258.xes_CO
    dc.relation.referencesGrubb, T. (2010). What Do We Really Know About the Drugs We Use to Treat Chronic Pain?. Topics in Companion Animal Medicine, 25(1), 10–19. doi: 10.1053/j.tcam.20 09 .10.001es_CO
    dc.relation.referencesHall, E y K Simpson (2000). Diseases of the Small Intestine. In S Ettinger and E Feldman (7 Ed.), Textbook of Veterinary Internal Medicine: Diseases of the Dog and Cat. (pp. 1182– 1238) Philadelphia: WB Saunders.es_CO
    dc.relation.referencesHall, J. y R. Washabau (2000). Gastric Prokinetic Agents. In J Bonagura (13 Ed.), Kirk’s Current Veterinary Therapy: XIII Small Animal Practice (pp. 609–617). Philadelphia: WB Saunders.es_CO
    dc.relation.referencesHardie, E. (2000). Therapeutic Mangement of Sepsis. In J Bonagura (13 Ed.), Kirk’s Current Veterinary Therapy: XIII Small Animal Practice (pp. 272–275). Philadelphia: WB Saunders.es_CO
    dc.relation.referencesHayes HM, Tarone RE, Cantor KP, Jessen R, McCurnin DM and Richardson RC. (1991). Case- control study of canine malignant lymphoma: Positive association with dog owner’s use of 2, 4-dichlorophenoxyacetic acid herbicides. J Natl Cancer Inst, 83(17), 1226–1231. doi: 10.1093/jnci/83.17.1226es_CO
    dc.relation.referencesHeel (2015). Homeopatía veterinaria. Guía Práctica Línea Veterinaria Heel. Recuperado de http://argos.portalveterinaria.com/revistasonline/espPropet2015 /archivos/heel_ vademecum.pdfes_CO
    dc.relation.referencesHenry, C. & M. Higginbotham (2009). Cancer Management in Small Animal Practice. Philadelphia: WB Saunders.es_CO
    dc.relation.referencesHoskins, J. (2001). Confirmation needed for lymphoma. Biological & Agricultural DVM, 32, 16S-20S. Recuperado de http://www.scielo.br/scielo.php?script=sci_nlinks&ref=000083& pid=S0103-8478201100070002200009&lng=ptes_CO
    dc.relation.referencesKeller ET. (1992). Immune-mediated disease as a risk factor for canine lymphoma. Cancer, 70(9), 2334–2337. doi: 10.1002/1097-0142(19921101)70:9<2334::AID-CNCR2820700920> 3.0.CO;2-7es_CO
    dc.relation.referencesKrohne SDG, Vestre WA, Richardson RC. (1987). Ocular involvement in canine lymphosarcoma: A retrospective study of 94 cases. Am College Vet Ophth Proc, 68–84.es_CO
    dc.relation.referencesKruth, S.A.; Carter, R.F. (1990). Laboratory abnormalities in patients with cancer. Veterinary Clinics of North America Small Animal Practice, 20(4), 897-917. Recuperado de https:// www. sciencedirect.com/journal/veterinary-clinics-of-north-america-small-animal- practice/vol/20/issue/4es_CO
    dc.relation.referencesLappin, M. (October of 2006). Giardia infections. In WSAVA , the World Small Animal Veterinary Association World Congress Proceedings. Praga, Czech Republic. Recuperado de https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11223&meta=Generic&catId =31443&id=3858918&ind=260&objTypeID=17es_CO
    dc.relation.referencesLappin, M (2000). Protozoal and Miscellaneous Infections. In S Ettinger and E Feldman (7 Ed.), Textbook of Veterinary Internal Medicine: Diseases of the Dog and Cat. (pp. 408–417). Philadelphia: WB Saunders.es_CO
    dc.relation.referencesMadewell BR, Feldman BF. (1980). Characterization of anemias associated with neoplasia in small animals. J Am Vet Med Assoc, 176(5), 419–425. Recuperado de https://www.ncbi.nlm. nih.gov/pubmed/6892634es_CO
    dc.relation.referencesMacEwen, EG, Patnaik AK, Wilkins RJ. (1977). Diagnosis and treatment of canine hematopoietic neoplasms. Vet Clin North Am (Small Anim Pract), 7, 105–118.es_CO
    dc.relation.referencesMassa KL, Gilger BC, Miller TL and Davidson MG. (2002). Causes of uveitis in dogs: 102 cases (1989-2000). Vet Ophthalmol, 5(2), 9–98. doi: 10.1046/j.1463-5224.2002.00217.xes_CO
    dc.relation.referencesMatthewman, L.A., Kelly, P.J., Brouqui, P. y Raoult, D. (1994). Further evidence for the efficacy of imidocarb dipropionate in the treatment of Ehrlichia canis infection. Journal of the South African Veterinary Association, 65(3), 104-107. Recuperado de https://www. ncbi.nlm.nih.gov/pubmed/7595915es_CO
    dc.relation.referencesMcCaw DL, Chan AS, Stegner AL, Mooney B, Bryan J, Turnquist S, Henry C, Alexander H and Alexander S. (2007). Proteomics of canine lymphoma identifies potential cancer-specific protein markers. Clin Cancer Res, 13(8), 2496–2503. doi: 10.1158 / 1078-0432.CCR-06- 2699es_CO
    dc.relation.referencesMcClure JC, Crothers ML, Schaefer JJ, Stanley PD, Needham GR, Ewing SA, et al. (2010). Efficacy of a doxycycline treatment regimen initiated during three different phases of experimental ehrlichiosis. Antimicrob Agents Chemother, 54(12), 5012–5020. doi: 10.1128 / AAC.01622-09es_CO
    dc.relation.referencesMilman G, Smith KC, Erles K. (2011). Serological detection of Epstein-Barr virus infection in dogs and cats. Vet Microbiol, 150(1-2), 15–20. doi: 10.1016/j.vetmic.2010.12.013es_CO
    dc.relation.referencesMorgan, RV, Ed. (1988). Handbook of Small Animal Practice. New York, United states: Churchill Livingstone.es_CO
    dc.relation.referencesMorrison, W.B. (2005). Lymphoma in dogs and cats. Jackson: Teton NewMedia.es_CO
    dc.relation.referencesNyman HT, Lee MH, McEvoy FJ, Nielsen O, Martinussen T and Kristensen A. (2006). Comparison of B-mode and Doppler ultrasonographic findings with histologic features of benign and malignant superficial lymph nodes in dogs. Am J Vet Res, 67(6), 978–984. doi: 10.2460 / ajvr.67.6.978es_CO
    dc.relation.referencesPapich, M. (1992). Table of Common Drugs: Approximate Dosages. In R Kirkand J Bonagura (11 Ed.), Current Veterinary Therapy XI: Small Animal Practice (pp. 1233-1249). Philadelphia: W.B. Saunders Company.es_CO
    dc.relation.referencesPeres, Y. (2000). Hyponatremia and hypokalemia. In S Ettinger and E Feldman (7 Ed.) Textbook of Veterinary Internal Medicine: Diseases of the Dog and Cat (pp. 222–227). Philadelphia: WB Saunders.es_CO
    dc.relation.referencesPhillips, R.W. (1988). Water-soluble Vitamins. In NH Booth and LE McDonald (6 Ed.), Veterinary Pharmacology and Therapeutics (pp. 698-702). Ames, Iowa State University.es_CO
    dc.relation.referencesPlumb, D.C. (2011). Plumb's veterinary drug handbook. Stockholm, Wisconsin PharmaVet inc (pp 35-3693).es_CO
    dc.relation.referencesPonce F, Magnol JP, Marchal T, Chabanne L, Ledieu D, Bonnefont C, Felman P and Fournel- Fleury C. (2003). High-grade T-cell lymphoma/ leukemia with plasmacytoid morphology: a clinical pathological study of nine case. J Vet Diagn Invest, 15(4), 330–337. doi: 10.1177 / 104063870301500405es_CO
    dc.relation.referencesPriester WA, McKay FW. (1980). The occurrence of tumors in domestic animal. Nat Cancer Inst Monogr, 54, 1–210. Recuperado de https://www.ncbi.nlm.nih.gov/pubmed/7254313es_CO
    dc.relation.referencesRatcliffe L, Mian S, Slater K, King H, Napolitano M, Aucoin D and Mobasheri A. (2009). Proteomic identification and profiling of canine lymphoma patients. Vet Comp Oncol, 7(2), 92–105. doi: 10.1111/j.1476-5829.2009.00165.xes_CO
    dc.relation.referencesReif JS, Lower KS, Ogilvie GK. (1995). Residential exposure to magnetic felds and risk of canine lymphoma. Am J Epidemiol, 141(4), 352–359. doi: 10.1093/aje/141.4.352es_CO
    dc.relation.referencesSchaefer JJ, Kahn J, Needham GR, Rikihisa Y, Ewing SA, Stich RW. (2008). Antibiotic clearance of Ehrlichia canis from dogs infected by intravenous inoculation of carrier blood. Ann N Y Acad Sci., 1149, 263–9. doi: 10.1196/annals.1428.087es_CO
    dc.relation.referencesSchoeman, J.P. (2009). Canine babesiosis. Onderstepoort Journal of Veterinary Research, 76, 59–66. Recuperado de https://pdfs.semanticscholar.org/d75b/24a8f852234a97180629e 9bae23d58f7ec7f.pdfes_CO
    dc.relation.referencesSozmen M, Tasca S, Carli E, Lorenzi D, Furlanello T and Caldin M. (2005). Use of fine needle aspirates and flow cytometry for the diagnosis, classification, and immunophenotyping of canine lymphomas. J Vet Diagn Invest, 17(4), 323–330. doi: 10.1177 / 104063870501700404es_CO
    dc.relation.referencesSueiro FA, Alessi AC, Vassallo J. (2004). Canine lymphomas: a morphological and immunohistochemical study of 55 cases, with observations on p53 immunoexpression. J Comp Pathol, 131(2-3), 207– 213. doi: 10.1016 / j.jcpa.2004.04.002es_CO
    dc.relation.referencesStarrak GS, Berry CR, Page RL, Johnsson JL and Thrall DE. (1997). Correlation between thoracic radiographic changes and remission/survival duration in 270 dogs with lymphosarcoma. Vet Radiol Ultrasound, 38(6), 411–418. doi: 10.1111/j.1740- 8261.1997.tb00863.xes_CO
    dc.relation.referencesTrepanier, L. (2010). Acute Vomiting In Cats Rational treatment selection. Journal of Feline Medicine and Surgery 12(3), 225–230. doi: 10.1016/j.jfms.2010.01.005es_CO
    dc.relation.referencesVail DM, Kravis LD, Kisseberth WC, Ogilvie G and Volk L. (1997). Application of rapid CD3 immunophenotype analysis and argyrophilic nucleolar organizer region (AgNOR) frequency to fine needle aspirate specimens from dogs with lymphoma. Vet Clin Pathol, 26(2), 66–69. doi: 10.1111/ j.1939-165X.1997.tb00711.xes_CO
    dc.relation.referencesVail, D.M.; Young, K.M. (2007). Canine lymphoma and lymphoid leukemia. In Withrow, S.J.; Vail, D.M. (4 Ed.), Withrow & MacEwen’s small animal clinical oncology (pp. 699-733). Philadelphia: W. B. Saunders Company.es_CO
    dc.relation.referencesValli, VE, Kass, PH, San Myint, M. y Scott, F. (2013). Canine lymphomas: association of classification type, disease stage, tumor subtype, mitotic rate, and treatment with survival. Vet Pathol, 50(5), 738-748. doi: 10.1177 / 0300985813478210es_CO
    dc.relation.referencesVeldhoen N, Stewart J, Brown R and Milner J. (1998). Mutations of the p53 gene in canine lymphoma and evidence for germ line p53 mutations in the dog. Oncogene, 16, 249–255. doi: 10.1038/ sj.onc.1201489es_CO
    dc.relation.referencesWilkerson MJ, Dolce K, Koopman T, Shuman W, Chun R, Garret L, Barber L and Avery A. (2005). Lineage differentiation of canine lymphoma/leukemias and aberrant expression of CD molecules. Vet Immunol Immunopathol, 106(3-4), 179–196. doi: 10.1016/j.vetimm.2005.02.020es_CO
    dc.relation.referencesWilson CR, Regnier FE, Knapp DW, Raskin E, Andrews D and Hooser S. (2008). Glycoproteomic profling of serum peptides in canine lymphoma and transitional cell carcinoma. Vet Comp Oncol, 6(3),171–181. doi: 10.11 11/j.1476-5829.2008.00158.xes_CO
    dc.relation.referencesZandvliet M. (2016). Canine lymphoma: a review. Veterinary Quarterly, 36(2), 76-104. doi: 10.1080/01652176.2016.1152633es_CO
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