Construcción de una base de datos espectrales de referencia mediante atr-ftir, para la identificación de sustancias controladas en Colombia.

Abstract

In Colombia, the production of illicit drugs continues to be a factor with a high impact on the country’s internal conflict, which has forced the authorities to intensify controls on controlled chemicals, which are fundamental during the synthesis of psychoactive substances. In accordance with the foregoing, this investigation, carried out in conjunction with the Office of the Attorney-General of the Nation, created a spectral reference database for controlled chemicals, as established in resolution 0001 of 8 January 2015 in the national territory, all in order to establish a theoretical basis on the spectral information of each substance analyzed by ATR-FTIR. First, samples provided by the Office of the Prosecutor were taken and analyzed with ATR-FTIR to determine the chemical profile of each substance, and multivariate tools such as PCA and HAC were used to determine differences between commercial samples; finally, an R&R analysis was performed to evaluate the variability in the spectra of the substances studied when changing analyst. In the results obtained highlights the spectral database, which was supported by a chemical profiling of each substance, showing the characteristic assignments of each chemical analyzed. The discrimination of cement, thinner and gasoline samples according to their first-order spectral information was also observed as it presented the greatest explanation for variance; to finalize and give statistical reliability to the research, it was found that in the study of variation of measures by R&R analysis, the value of contribution to the variance of the study (9.37%) is below the 10% threshold.