Asociación diabetes mellitus tipo 2 y tuberculosis en los pacientes que asisten a las IPS de Imsalud de la zona Atalaya en Cúcuta (Norte de Santander) en el período comprendido entre enero de 2013 a diciembre de 2015.

Abstract

Objective: To establish the association between diabetes mellitus type 2 (DM2) and pulmonary tuberculosis (TB) in patients attending the outpatient service in IPS Watchtower IMSALUD area of Cucuta, Norte de Santander. Materials and methods: An observational, analytical study of such cases and controls was performed; where all patients who attended the IPS IMSALUD of Atalaya area (Norte de Santander) from January 2013 to December 2015 (28,015 patients) were selected. The medical records of patients with diagnosis of TB (100) and the consolidated diabetic patients (847) was obtained from the database IMSALUD. Results: Of a total population of 28,015 patients; 100 (0.4%) and 847 (3%) patients were diagnosed with TB and DM2 respectively. Of the 100 patients with TB, 17 (0.1%) had a diagnosis of DM2 time. The statistical association (chi square) for type 2 diabetes and TB variables, reported a 66.8 result for p <0.05 (CI: 5.1-8.3). Conclusions: The literature suggests that there is increased susceptibility in people with DM2 of contracting TB and that this can be explained by defects in cellular immunity caused by periods of hyperglycemia in addition to altering the function of leukocytes polimorfonucleares8. In this study, a significant association binomial DM2-TB was established, reporting that there is a risk (OR) 6.7 times more likely to develop TB in patients with a history of type 2 diabetes than those without such comorbidity.